Bipolar Disorder Treatment · York, PA
Stabilize the highs, lift the lows. Stay yourself.
Bipolar Disorder Treatment in York, PA: Diagnosis and Mood Stabilizer Care
Bipolar disorder needs steady, expert follow-up. At Optimal Health York in downtown York,PA, board-certified psychiatric nurse practitioners diagnose bipolar I and II, prescribe and monitor mood stabilizers, and begin therapy in your visits. Zainab Koroma sees patients in person or by telehealth in PA and MD. Abu Koroma sees patients by telehealth in PA, MD and VA. New patients are typically seen within a week. Call (717) 202-2285.
- Bipolar I Disorder
- Bipolar II Disorder
- Cyclothymic Disorder
- Mixed Features
- Rapid Cycling
- Bipolar with Anxiety
Optimal Health York treats bipolar disorder at 111 East Market Street in York, PA. Board-certified psychiatric nurse practitioners provide diagnosis, mood stabilizer treatment with medication and lab monitoring, and therapy within visits, in person or by telehealth. New patients are typically seen within a week. We accept all major insurances. Call today to confirm your insurance. (717) 202-2285. Call (717) 202-2285 or book online.
A serious, recurrent — and highly treatable — mood disorder
Bipolar disorder — sometimes called manic-depressive illness — is a serious mood disorder characterized by dramatic shifts in mood, energy, and activity levels. According to the National Institute of Mental Health, an estimated 2.6% of U.S. adults — about 5.7 million Americans — have bipolar disorder in any given year, with 82.9% experiencing serious impairment — the highest rate among mood disorders. The National Comorbidity Survey Replication (NCS-R) found lifetime prevalence of 1.0% for Bipolar I, 1.1% for Bipolar II, and 2.4% for sub-threshold bipolar — about 4.4% of adults across the bipolar spectrum.
The median age of onset is 25, but bipolar disorder can start in adolescence or later in life. It runs strongly in families: roughly two-thirds of people with bipolar disorder have a close relative with bipolar or major depression, per the Depression and Bipolar Support Alliance. Despite how serious bipolar disorder is, treatment works — with the right combination of medication and support, most people achieve sustained mood stability.
At Optimal Health York, bipolar disorder treatment is delivered by board-certified Psychiatric Mental Health Nurse Practitioners (PMHNP-BC) using the same evidence-based standards recommended by the American Academy of Family Physicians, the CANMAT/ISBD 2018 guidelines (2023 update), and the American Psychiatric Association: mood stabilizers, atypical antipsychotics, and psychotherapy begun within your visits, with treatment tailored to acute mania, bipolar depression, or long-term maintenance. You can be seen in person at our York office or via telehealth across Pennsylvania, Maryland, and Virginia. New patient appointments are typically available within one week. We accept all major insurances. Call today to confirm your insurance. (717) 202-2285.
The 6 most common bipolar presentations
DSM-5 recognizes several distinct bipolar conditions, plus specifiers for mood episode features. We evaluate and treat all of them at Optimal Health York.
| Presentation | U.S. lifetime prevalence | Key features |
|---|---|---|
| Bipolar I Disorder | ~1.0% lifetime | At least one full manic episode (7+ days, or any duration if hospitalization required). Depressive episodes typical but not required for diagnosis. |
| Bipolar II Disorder | ~1.1% lifetime | At least one hypomanic episode (4+ days, less severe than mania) plus at least one major depressive episode. Often misdiagnosed as unipolar depression. |
| Cyclothymic Disorder | ~2.4% sub-threshold | Chronic mood instability lasting 2+ years (1+ year in children/teens), with hypomanic and depressive symptoms not meeting full criteria for either. |
| Mixed Features (specifier) | ~30–40% of episodes | Symptoms of both mania and depression in the same episode — e.g., agitation with sadness, racing thoughts with hopelessness. Higher suicide risk. |
| Rapid Cycling (specifier) | ~10–20% of bipolar patients | 4 or more mood episodes (manic, hypomanic, or depressive) in 12 months. More common in Bipolar II; harder to stabilize. |
| Bipolar with Anxiety | ~50% co-occurrence | Bipolar disorder co-occurring with generalized anxiety, panic, or social anxiety. Treatment plan must avoid worsening mood instability. |
Sources: National Institute of Mental Health · Merikangas et al, NCS-R Bipolar Spectrum Prevalence · Depression and Bipolar Support Alliance · AAFP Bipolar Disorders: Evaluation and Treatment.
What bipolar disorder looks and feels like
Bipolar disorder cycles between mood episodes. A manic episode requires elevated or irritable mood plus 3+ symptoms (4+ if irritable only) lasting 7+ days; a hypomanic episode is similar but milder and lasts 4+ days. Major depressive episodes share the same criteria as unipolar depression.
Manic / hypomanic symptoms
- Elevated, expansive, or irritable mood nearly every day
- Inflated self-esteem or grandiosity
- Decreased need for sleep (e.g., feels rested after 3 hours)
- More talkative than usual or pressure to keep talking
- Racing thoughts or flight of ideas
- Distractibility — attention pulled by every passing stimulus
- Increased goal-directed activity or psychomotor agitation
- Risky behavior — spending sprees, sexual indiscretion, reckless driving
- In severe cases: psychotic symptoms (delusions, hallucinations)
Depressive episode symptoms
- Persistent sad or empty mood most of the day
- Loss of interest or pleasure in usual activities
- Significant weight or appetite changes
- Sleep changes — insomnia or sleeping excessively
- Fatigue or loss of energy nearly every day
- Feelings of worthlessness or excessive guilt
- Diminished ability to think, concentrate, or make decisions
- Psychomotor slowing or agitation
- Recurrent thoughts of death or suicide — if present, seek help today
Diagnosis requires a thorough clinical interview, often supplemented by validated rating scales like the Mood Disorder Questionnaire (MDQ) for screening or the Young Mania Rating Scale (YMRS) to track mania severity. This page is not a diagnostic tool — bipolar disorder is frequently misdiagnosed (often as unipolar depression for years), so a careful evaluation is essential. If you're having thoughts of suicide or self-harm, call or text 988 (Suicide & Crisis Lifeline) or go to your nearest emergency room. Bipolar disorder carries a 15–20% lifetime suicide risk when untreated — treatment dramatically reduces this risk, particularly with lithium.
The evidence-based bipolar treatment hierarchy
Bipolar treatment is phase-specific — what works for mania differs from what works for bipolar depression. We follow the protocols in the AAFP Bipolar Disorders guideline and the CANMAT/ISBD recommendations.
Acute mania: lithium, valproate, or atypical antipsychotic
First-line treatments for an acute manic episode include lithium, valproate (Depakote), and atypical antipsychotics — quetiapine, aripiprazole, risperidone, asenapine, paliperidone, or cariprazine — as monotherapy. Combination therapy (mood stabilizer plus an atypical antipsychotic) often works faster and is recommended for severe or psychotic mania. Hospitalization may be necessary for safety in severe episodes.
Bipolar depression: lurasidone, quetiapine, lamotrigine, or lithium
Bipolar depression is treated differently from unipolar depression. First-line options per APA and CANMAT/ISBD include lurasidone (Latuda), quetiapine, lamotrigine, and lithium. The combination of olanzapine plus fluoxetine (Symbyax) is also FDA-approved. SSRIs alone should generally be avoided in bipolar depression — they can trigger manic switching or rapid cycling. If antidepressants are used, they're typically combined with a mood stabilizer.
Maintenance: long-term mood stabilization
Lithium remains the most evidence-based maintenance treatment per long-term studies spanning 70+ years, with the unique benefit of reducing suicide risk. Other first-line maintenance options include lamotrigine (especially for depressive prevention), valproate, and the atypical antipsychotic that worked in the acute phase. Maintenance treatment is typically indefinite — relapse rates are high without it.
Psychotherapy & lifestyle — essential adjuncts
Medication is the foundation, but psychotherapy meaningfully improves outcomes. Evidence-based options include cognitive-behavioral therapy (CBT), interpersonal and social rhythm therapy (IPSRT), family-focused therapy, and psychoeducation. We begin psychotherapy within your visits — psychoeducation, early-warning-sign tracking, and CBT-based skills, with no separate therapy bill — and work on the lifestyle factors that compound or buffer mood instability: sleep regularization (critical for bipolar), substance avoidance, stress management, and daily routine. When a structured program like IPSRT or family-focused therapy is the right fit, we refer to bipolar-specialized therapists.
In-person in York — or telehealth from home
Both options use the same providers and the same evidence-based treatment protocols. Pick whichever fits your week.
In-person at the York office
- With Zainab Koroma, PMHNP-BC, FNP-C — psychiatric care plus primary care, ages 8 and up
- With Abu Koroma, PMHNP-BC, CRNA on — ages 12 and up
- Best for first-time evaluations and patients new to psychiatric care
- Saturday: 10:00 AM – 2:00 PM
Telehealth (PA, MD, VA)
- With Abu Koroma, PMHNP-BC, CRNA (PA, MD, VA, ages 12+) or Zainab (PA, MD, ages 8+)
- Best for routine medication management and busy schedules
- Prescriptions sent to your local pharmacy · HIPAA-compliant patient portal
Common questions about bipolar disorder treatment
What is the most effective treatment for bipolar disorder?
The most effective bipolar disorder treatment is long-term mood stabilizer medication, often combined with an atypical antipsychotic and psychotherapy. Lithium remains the most evidence-based maintenance treatment — with the unique benefit of reducing suicide risk — per international guidelines including AAFP, APA, and CANMAT/ISBD.
For acute mania, first-line options include lithium, valproate, and atypical antipsychotics (quetiapine, aripiprazole, risperidone). For bipolar depression, first-line options include lurasidone, quetiapine, lamotrigine, and lithium. Treatment is tailored to the current phase and continued indefinitely because of the high relapse risk.
Can a psychiatric NP treat bipolar disorder in Pennsylvania?
Yes. Psychiatric Mental Health Nurse Practitioners (PMHNP-BC) are licensed in Pennsylvania to diagnose bipolar disorder, prescribe mood stabilizers (lithium, valproate, lamotrigine, carbamazepine), atypical antipsychotics, and other psychotropic medications — working under Pennsylvania's collaborative-practice requirements for nurse practitioners — and provide psychotherapy. PMHNPs complete a master's or doctoral degree in psychiatric mental health nursing and pass a national board certification exam.
For most outpatient bipolar care, a PMHNP-BC provides comparable treatment to a psychiatrist — with typically shorter wait times. Both providers at Optimal Health York are board-certified PMHNPs. Severely complex or treatment-resistant bipolar cases may benefit from specialty consultation, which we facilitate when indicated.
What's the difference between bipolar I and bipolar II?
Bipolar I requires at least one full manic episode — 7 or more days of elevated, expansive, or irritable mood with significant functional impairment, or any duration severe enough to require hospitalization. Depressive episodes typically also occur but aren't required for the diagnosis.
Bipolar II requires at least one hypomanic episode plus at least one major depressive episode — never a full manic episode. Hypomania is shorter (4+ days) and less severe than mania, often experienced as productive or pleasant by the person. Bipolar II is frequently misdiagnosed as unipolar depression because patients tend to seek help during depressive episodes, not hypomanic ones.
How long does it take for bipolar medication to work?
Timing depends on the phase being treated. For acute mania, atypical antipsychotics (quetiapine, olanzapine) often produce noticeable improvement within days to a week. Lithium and valproate typically require 1–3 weeks for full mood-stabilizing effect.
For bipolar depression, lurasidone and quetiapine work within 2–6 weeks. Lamotrigine requires slow titration over 6–8 weeks because of skin rash risk — the dose is increased gradually to therapeutic levels. Long-term maintenance benefits accumulate over months. We schedule close 30-minute follow-ups during titration to monitor response, side effects, and relevant blood levels (lithium, valproate, lamotrigine).
Is bipolar disorder treatment covered by insurance?
Yes — bipolar disorder evaluation and treatment is covered by all major insurance plans under federal mental health parity laws. We accept all major insurances. Call today to confirm your insurance. (717) 202-2285.
Most patients pay only their plan's specialist copay (typically $20–60). Self-pay rates are $249 for an initial evaluation and $99 for medication management follow-ups; psychotherapy begun within your visit is not billed separately. HSA, FSA, cash, credit card, and check accepted. Note: some bipolar medications — especially lithium — require periodic blood tests (lithium level, kidney function, thyroid), which are billed separately by your lab.
Can I get bipolar disorder treatment via telehealth in PA, MD, or VA?
Yes. We provide full bipolar disorder treatment via telehealth across Pennsylvania, Maryland, and Virginia, including evaluations, medication management, and follow-up visits. Federal and state laws allow PMHNPs to prescribe mood stabilizers and atypical antipsychotics via telehealth.
You must be physically located in a state where your provider is licensed at the time of the visit. Abu Koroma sees patients in PA, MD, and VA (ages 12+); Zainab Koroma sees patients in PA and MD (ages 8+) including in-person at York. Note: patients on lithium or valproate need periodic blood draws at a local lab — we coordinate ordering and review results remotely.
Is lithium safe? What about side effects and blood tests?
Lithium has a strong safety record across nearly 70 years of clinical use when properly monitored. The most common side effects are mild tremor, increased thirst and urination, weight changes, and acne; less common but more serious are kidney and thyroid effects with long-term use. Lithium has a narrow therapeutic window, so blood levels and labs must be monitored regularly — we check serum lithium levels every 3–6 months once stable, and kidney and thyroid function every 6–12 months.
The trade-off is real: lithium is the only medication shown to significantly reduce suicide risk in bipolar disorder — an outcome no other mood stabilizer has matched. For many patients, this benefit is decisive. We discuss the risk-benefit balance carefully when deciding whether lithium fits your situation.
Can antidepressants make bipolar disorder worse?
Yes — this is one of the most important reasons bipolar disorder needs accurate diagnosis. Antidepressants used alone (without a mood stabilizer) can trigger manic switching, mixed episodes, or rapid cycling in people with bipolar disorder. This is why bipolar depression is treated differently from unipolar depression.
If antidepressants are used in bipolar disorder, they're typically combined with a mood stabilizer or atypical antipsychotic, used at lower doses, and tapered off when the depressive episode resolves. SSRIs alone are generally avoided. This is also why bipolar II is so frequently missed — patients are treated with antidepressants for what looks like recurrent depression, sometimes for years, before the bipolar pattern is recognized.
Do you treat bipolar disorder in children and teenagers?
Yes, with appropriate caveats. Zainab Koroma sees patients ages 8 and up at our York office and via telehealth in PA and MD. Abu Koroma sees ages 12 and up via telehealth in PA, MD, and VA. Pediatric bipolar disorder is complex to diagnose — symptoms often look different from adult bipolar (more irritability, less euphoria) and overlap with ADHD, ODD, and disruptive mood dysregulation disorder.
For diagnosed adolescent bipolar disorder, FDA-approved options include lithium, aripiprazole, risperidone, and quetiapine. We coordinate with parents, schools, and specialty pediatric psychiatry consultants when indicated. Children & adolescent care details.
How soon can I be seen for a bipolar disorder evaluation?
New patient appointments at Optimal Health York are typically available within one week. Bipolar evaluations are 60-minute initial visits, allowing time for thorough mood history, family history, and ruling out other conditions; follow-ups are 30 minutes. Same-day and next-day telehealth appointments are often available depending on provider schedule. Call (717) 202-2285 to check current availability, or book online 24/7 through our HIPAA-compliant patient portal.
If you're in a manic or mixed episode with safety concerns, or having thoughts of suicide or self-harm, don't wait — call or text 988 (Suicide & Crisis Lifeline), call 911, or go to your nearest emergency room.
Sources & references
- National Institute of Mental Health. Bipolar Disorder — Statistics. Accessed 2026.
- Merikangas KR, et al. Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey Replication. Archives of General Psychiatry.
- Bobo WV. Bipolar Disorders: Evaluation and Treatment. American Family Physician, 2021.
- Yatham LN, et al. The CANMAT and ISBD Guidelines for the Treatment of Bipolar Disorder: Summary and a 2023 Update of Evidence. Focus (American Psychiatric Association).
- Volkmann C, Bschor T, Köhler S. Lithium Treatment Over the Lifespan in Bipolar Disorders. Frontiers in Psychiatry, 2020.
- Depression and Bipolar Support Alliance. Bipolar Disorder Statistics.
- Post RM, Rybakowski JK. What Patients with Bipolar Disorder Need to Know about Lithium. Pharmaceuticals, 2024.
Bipolar treatment shouldn't be hard to access.
New patient appointments are typically available within a week. Book online any time, or call during office hours and a real person will pick up.